| Description | Chrysophanol triglucoside, an anthraquinone derivative obtained from Cassia obtusifolia, demonstrates inhibitory activity against protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase, with half-maximal inhibitory concentration (IC50) values of 80.17 μM and 197.06 μM, respectively. This compound exhibits potential for diabetes research. |
| Target activity | α-glucosidase:197.06 µM (IC50), PTP1B:80.17 µM (IC50) |
| molecular weight | 740.664 |
| Molecular formula | C33H40O19 |
| CAS | 120181-07-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Jung HA, et, al. Promising Inhibitory Effects of Anthraquinones, Naphthopyrone, and Naphthalene Glycosides, from Cassia obtusifolia on α-Glucosidase and Human Protein Tyrosine Phosphatases 1B. Molecules. 2016 Dec 27; 22(1): 28. |