| Description | Chromocarb (Chromone-2-carboxylic acid) is a vascular protective agent used to treat venous disorders and microvascular affections. |
| In vitro | 用Chromocarb口服治疗的大鼠,静脉胶原酶引起的血管壁的降解明显降低. Chromocarb治疗可以诱导BBB渗透性增加减少,恢复时间缩短,脑脊液中较低的羟脯氨酸水平以及大脑毛细管基底膜中胶原含量的较少下降.50 mg/kg Chromocarbe比维生素C更有效地预防血液中还原型谷胱甘肽的氧化. |
| Synonyms | Chromone-2-carboxylic acid, 色烯卡, Chromocarbe |
| molecular weight | 190.15 |
| Molecular formula | C10H6O4 |
| CAS | 4940-39-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 50 mg/mL (262.95 mM) Ethanol: < 1 mg/mL (insoluble or slightly soluble) |
| References | 1. Godeau G, et al. Clin Physiol Biochem, 1987, 5(1), 15-26. 2. Márquez R, et al. Pharmacol Toxicol, 2001, 89(5), 255-258 |