| Description | Chol-N3 is a bioorthogonal chol probe capable of integrating with super-resolution fluorescence microscopy (SRM) to enable direct nanoscale imaging of lipid heterogeneity on resting living cell surfaces [1]. As a click chemistry reagent with an azide group, Chol-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN group-containing molecules. |
| In vitro | Chol-N3(25 μM; 16小时; 活的SH-SY5Y细胞)在维持细胞活性的实验条件下显示,该化合物在质膜(PM)中明确揭示了纳米尺度的结构域分布情况[1]。 |
| molecular weight | 385.59 |
| Molecular formula | C24H39N3O |
| CAS | 2106868-12-4 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |