| Description | Chloracyzine can produce a decrease in myocardial oxygen consumption accompanied by a reduction in coronary blood flow preceded by transient coronary dilatation. It produced an insignificant increase in arterial pressure; heart rate increased slightly in the open-chest experiments but not in the isolated heart. |
| Synonyms | Chloroacizine, Chloroacizin, Chlorazicine, Chloroacyzin |
| molecular weight | 360.9 |
| Molecular formula | C19H21ClN2OS |
| CAS | 800-22-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Kisin IE. On the decrease of myocardial oxygen consumption induced by chloracyzine. Br J Pharmacol. 1976 Oct;58(2):189-92. PubMed PMID: 974382; PubMed Central PMCID: PMC1667375. 2. Saratikov AS, Dmitrienko VF. Effects of papaverine, chloracyzine, and bencyclane on local blood flow and oxygen tension in cat brain. Cor Vasa. 1975;17(2):125-32. PubMed PMID: 1157501. 3. Saratikov AS, Usov LA, Voloshina E, Sakharova SA. The effect of chloracyzine upon cerebral circulation and some indices of cerebral metabolism. Cor Vasa. 1969;11(4):279-86. PubMed PMID: 5373324. 4. Parnev OM, Naumov OG, Ivkov NN, Vladimirov IuA. [Effect of phenothiazines on the viscosity and electrical stability of model phospholipid membranes]. Biull Eksp Biol Med. 1987 May;103(5):555-7. Russian. PubMed PMID: 3593924. |