| Description | CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2. |
| Target activity | GSK-3α:0.65 nM, GSK-3β:0.58 nM |
| Synonyms | CHIR98014 |
| molecular weight | 486.31 |
| Molecular formula | C20H17Cl2N9O2 |
| CAS | 556813-39-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 6.88 mg/mL (14.14 mM), Sonication is recommended. |
| References | 1. Ring DB,et al. Diabetes. 2003, 52(3), 588-595. |