Description | CD73-IN-3 (LY-3475070) is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer. |
Target activity | CD73:28 nM |
Synonyms | EX-A4254, LY-3475070 |
molecular weight | 286.33 |
Molecular formula | C15H18N4O2 |
CAS | 2375815-63-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 22.5 mg/mL (78.58 mM) |