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CD73-IN-3

CAS No.: 2375815-63-5

CD73-IN-3 (LY-3475070) is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combinati
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Description CD73-IN-3 (LY-3475070) is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.
Target activity CD73:28 nM
Synonyms EX-A4254, LY-3475070
molecular weight 286.33
Molecular formula C15H18N4O2
CAS 2375815-63-5
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 22.5 mg/mL (78.58 mM)