| Description | CCT365623 is an orally bioavailable Lysyl Oxidase inhibitor with good anti-LOX potency, selectivity, pharmacokinetic properties, as well as anti-metastatic efficacy. |
| Synonyms | CCT-365623, CCT 365623 |
| molecular weight | 407.53 |
| Molecular formula | C18H17NO4S3 |
| CAS | 2126134-01-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 4.08 mg/mL (10 mM) |
| References | 1. Tang H, et al. Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface. Nat Commun. 2017 Apr 18;8:14909. 2. Leung L, et al. Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure-Activity Relationships. J Med Chem. 2019 Jun 27;62(12):5863-5884. |