PeptideDB

CB2R-IN-1

CAS No.: 1257555-79-5

CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).
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Description CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).
In vitro CB2R-IN-1 (Compound 37) has excellent selectivity for cannabinoid CB2 receptor ligand with over the CB1 receptor (Ki: 8259.3 nM).
Target activity CB2:0.9 nM (ki)
molecular weight 608.67
Molecular formula C23H27F3N4O6S3
CAS 1257555-79-5
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Tong L, et al. Expansion of SAR studies on triaryl bis sulfone cannabinoid CB2 receptor ligands. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6785-9.