| Description | CAY10614 is a TLR4 antagonist. CAY10614 inhibits lipid A-induced activation of TLR4 (IC50=1.675 μM). CAY10614 also improves survival in LPS-induced shock model mice. |
| Target activity | TLR4:1.675 μM (IC50, in HEK293 cells) |
| Synonyms | CAY10614 |
| molecular weight | 755.995 |
| Molecular formula | C42H78INO2 |
| CAS | 1202208-36-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 0.14 mg/mL DMF: 0.15 mg/mL |