| Description | Casein kinase 1δ-IN-6 is a potent and selective inhibitor of the protein kinase CK-1δ with an IC50 of 23 nM.Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays.Casein kinase 1δ-IN-6 can be used to study neurodegenerative diseases. |
| Target activity | CK1δ:23 nM |
| molecular weight | 370.78 |
| Molecular formula | C16H10ClF3N2OS |
| CAS | 1579991-01-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (148.34 mM) |
| References | 1. Morales-Garcia JA, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease. ACS Omega. 2017;2(8):5215-5220. |