| Description | Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM). |
| Target activity | 5-HT1A receptor:2.6 nM (ki), D3 receptor:0.085 nM (ki), D2 receptor:0.49 nM (ki) |
| Synonyms | RGH-188 D6 |
| molecular weight | 433.45 |
| Molecular formula | C21H26D6Cl2N4O |
| CAS | 1308278-67-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Seneca N, et al. Occupancy of dopamine D2 and D3 and serotonin 5-HT1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography. Psychopharmacology (Berl). 2011 Dec;218(3):579-8 |