| Description | Carabrone, a botanical bicyclic sesquiterpenic lactone, is a promising fungicidal agent that can effectively control G. tritici. |
| In vitro | 为了不断提升天然先导化合物Carabrone在农化领域的潜在应用价值，本研究合成了Carabrone肟及其在C(4)位置修改的36个新型肟酯衍生物，并对其针对灰葡萄孢(Botrytis cinerea)的体内外抗真菌活性进行了评估[1]。 |
| Target activity | Colletotrichum lagenarium:7.10 μg/mL (EC50) |
| molecular weight | 248.32 |
| Molecular formula | C15H20O3 |
| CAS | 1748-81-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (241.62 mM) |
| References | 1. Wang D, et al. Semisynthesis and antifungal activity of novel oxime ester derivatives of carabrone modified at C(4) against Botrytis cinerea. Chem Biodivers. 2014 Jun;11(6):886-903. 2. Wang M, et al. A functional analysis of mitochondrial respiratory chain cytochrome bc1 complex in Gaeumannomyces tritici by RNA silencing as a possible target of carabrone. Mol Plant Pathol. 2020 Dec;21(12):1529-1544. |