| Description | Capecitabine-2',3'-cyclic Carbonate is a antiproliferative agent. |
| In vitro | Capecitabine-2',3'-cyclic Carbonate 通过抑制肿瘤细胞的增殖展现了其活性,其IC50值针对HeLa、MCF-7、PZ-HPV-7及NCI-69肿瘤细胞系分别为0.08mg/mL、0.08mg/mL、0.14mg/mL和0.18mg/mL[1]。 |
| molecular weight | 385.34 |
| Molecular formula | C16H20FN3O7 |
| CAS | 921769-65-5 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 27.5 mg/mL (71.36 mM) |
| References | 1. Jhansi Rani V, et al. Synthesis and biological activity evaluation of cytidine-5'-deoxy-5-fluoro-N-[(alkoxy/aryloxy)] carbonyl-cyclic 2',3'-carbonates. Eur J Med Chem. 2012 Aug;54:690-6. |