| Description | Calcimycin (A-23187) hemimagnesium, an antibiotic and divalent cation ionophore (such as calcium and magnesium), serves various biological roles. It triggers Ca2+-dependent cell death by elevating intracellular calcium levels and suppresses the growth of Gram-positive bacteria and certain fungi. Additionally, this compound hinders ATPase activity and uncouples oxidative phosphorylation (OXPHOS) in mammalian cells, ultimately leading to apoptosis [1] [2] [3] [4]. |
| molecular weight | 1069.53 |
| Molecular formula | C58H72MgN6O12 |
| CAS | 72124-77-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |