| Description | Cadralazine (ISF 2469) is a peripheral arteriolar vasodilator and can be used in studies about acting as an antihypertensive drug. |
| Synonyms | ISF 2469, 卡屈嗪, ISF-2469, ISF2469 |
| molecular weight | 283.33 |
| Molecular formula | C12H21N5O3 |
| CAS | 64241-34-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 200 mg/mL (705.9 mM), Sonication and heating to 60℃ are recommended. |
| References | 1. Ebihara A, Fujimura A. Metabolites of antihypertensive drugs. An updated review of their clinical pharmacokinetic and therapeutic implications. Clin Pharmacokinet. 1991 Nov;21(5):331-43. Review. 2. McTavish D, Young RA, Clissold SP. Cadralazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of hypertension. Drugs. 1990 Oct;40(4):543-60. Review. 3. K Takeyama, et al. Antihypertensive activity of cadralazine in experimental hypertensive rats. Arch Int Pharmacodyn Ther. Jan-Feb 1988;291:163-74. |