| Description | C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells. |
| Synonyms | C2 L-threo Ceramide (d18:1/2:0) |
| molecular weight | 341.53 |
| Molecular formula | C20H39NO3 |
| CAS | 143615-69-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMF: 5 mg/mL DMSO: Soluble Chloroform: Soluble Ethanol: Soluble |
C2 L-threo Ceramide (d18:1/2:0)
CAS No.: 143615-69-4
C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulate
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