| Description | c (phg-isoDGR- (NMe) k) is a selective and effective α5β1-integrin ligand with IC50 of 2.9 nM. |
| In vivo | c (phg-isoDGR- (NMe) k) was trimerized with the chelating agent TRAP and used as a positron emission tomography tracer to monitor the expression of α5β1 integrin in M21 mouse xenografts. |
| Target activity | α5β1:2.9 nM |
| molecular weight | 603.67 |
| Molecular formula | C27H41N9O7 |
| CAS | 1844830-65-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Kapp TG, et al. N-Methylation of isoDGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent. J Med Chem. 2018 Mar 22;61(6):2490-2499. |