| Description | C-NH-Boc-C-Bis-(C1-PEG1-PFP) is a polyethylene glycol (PEG)-derived PROTAC linker, which finds application in the synthesis of PROTACs[1]. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 667.45 |
| Molecular formula | C26H23F10NO8 |
| CAS | 1807521-01-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
C-NH-Boc-C-Bis-(C1-PEG1-PFP)
CAS No.: 1807521-01-2
C-NH-Boc-C-Bis-(C1-PEG1-PFP) is a polyethylene glycol (PEG)-derived PROTAC linker, which finds application in the synthe
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