| Description | Bulgecin C is an O-sulfonated glycopeptides that can enhance the antibacterial activity of beta-lactam antibiotics. |
| molecular weight | 444.41 |
| Molecular formula | C14H24N2O12S |
| CAS | 92953-56-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Thunnissen AM, Rozeboom HJ, Kalk KH, Dijkstra BW. Structure of the 70-kDa soluble lytic transglycosylase complexed with bulgecin A. Implications for the enzymatic mechanism. Biochemistry. 1995 Oct 3;34(39):12729-37. PubMed PMID: 7548026. 2. Karlsen S, Hough E. Structure of a complex between bulgecin, a bacterial metabolite, and lysozyme from the rainbow trout. Acta Crystallogr D Biol Crystallogr. 1996 Jan 1;52(Pt 1):115-23. PubMed PMID: 15299732. 3. Karlsen S, Hough E, Rao ZH, Isaacs NW. Structure of a bulgecin-inhibited g-type lysozyme from the egg white of the Australian black swan. A comparison of the binding of bulgecin to three muramidases. Acta Crystallogr D Biol Crystallogr. 1996 Jan 1;52(Pt 1):105-14. PubMed PMID: 15299731. 4. Fibriansah G, Gliubich FI, Thunnissen AM. On the mechanism of peptidoglycan binding and cleavage by the endo-specific lytic transglycosylase MltE from Escherichia coli. Biochemistry. 2012 Nov 13;51(45):9164-77. doi: 10.1021/bi300900t. Epub 2012 Oct 30. PubMed PMID: 23075328. |