| Description | BuChE-IN-9 (compound 22a), an eqBuChE (equine serum-derived butyrylcholinesterase) inhibitor, exhibits potent activity with an IC50 of 173 nM. In addition to eqBuChE, it also inhibits human BACE1, Aβ aggregation, and mouse GABA transporters 1 and 4 (mGAT1 and mGAT4). Notably, BuChE-IN-9 demonstrates significant antiamnesic properties [1]. |
| molecular weight | 458.6 |
| Molecular formula | C28H34N4O2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |