| Description | Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL. |
| In vitro | 一种基于绿色荧光蛋白(GFP)标记的辣椒斑驳病毒(PepMoV)叶盘法和系统寄主法被开发出来,用以鉴定抗病毒化合物。通过使用PepMoV-GFP标记的叶盘法进行的初步实验,从鸦胆子(Brucea javanica)的CH3OH提取物中分离出了五种苦木素类化合物,包括苦烯酮(1)、苦参素(2)、鸦胆素A(3)、Bruceantinol(4)和鸦胆素B(5)。[1] |
| molecular weight | 606.61 |
| Molecular formula | C30H38O13 |
| CAS | 53729-52-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (90.67 mM) |
| References | 1. Quassinoids isolated from Brucea javanica inhibit pepper mottle virus in pepper.Virus Res. 2017 Jan 2;227:49-56. |