| Description | Bruceantin (NSC-165563) is a natural product isolated from Brucea antidysenterica. Bruceantin has antitumor activity against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice. |
| In vivo | Bruceantin 在早期及晚期肿瘤中诱导了退化，并且在没有明显毒性的情况下促进了这些显著的抗肿瘤反应。 |
| Synonyms | 鸦胆亭, (-)-Bruceantin, NCI165563, 鸦胆停, NSC165563 |
| molecular weight | 548.58 |
| Molecular formula | C28H36O11 |
| CAS | 41451-75-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: Soluble |
| References | 1. Cuendet M, et al. Antitumor activity of bruceantin: an old drug with new promise. J Nat Prod. 2004 Feb;67(2):269-72. 2. Cuendet M, et al. Multiple myeloma regression mediated by bruceantin. Clin Cancer Res. 2004 Feb 1;10(3):1170-9. |