| Description | Bromo-PEG2-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1]. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 333.16 |
| Molecular formula | C10H22BrO5P |
| CAS | 1226767-94-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
Bromo-PEG2-phosphonic acid diethyl ester
CAS No.: 1226767-94-7
Bromo-PEG2-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysi
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