| Description | Briquilimab (JSP-191), a non-toxic humanized monoclonal antibody, targets CD117 (c-Kit) to deplete hematopoietic stem cells (HSCs), providing a safe approach for clearing host marrow niche to facilitate adequate donor HSC engraftment and immune reconstitution, primarily in the treatment of severe combined immunodeficiency (SCID) [1]. |
| Synonyms | JSP-191 |
| molecular weight | N/A |
| CAS | 2574591-89-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 years |