| Description | Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess interesting breast cancer resistance protein inhibitory activity. |
| Target activity | PI3Kα:4.8 μM (IC50) |
| Synonyms | Cyclo-L-tryptophyl-L-proline, cyclo-(L-Trp-L-Pro), Cyclo(L-Pro-L-Trp) |
| molecular weight | 283.33 |
| Molecular formula | C16H17N3O2 |
| CAS | 38136-70-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (176.47 mM), Sonication is recommended. |
| References | 1. Borthwick AD. Chemical Reviews. 2012. 112 (7): 3641–3716. |