| Description | BRD-IN-3 is a highly potent PCAF bromodomain (BRD) inhibitor (IC50: 7 nM). It also exhibits activity against GCN5 and FALZ. |
| Target activity | PCAF BRD: |
| molecular weight | 395.45 |
| Molecular formula | C21H25N5O3 |
| CAS | 2351938-32-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Huang L, et al. Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. J Med Chem. 2019 May 9;62(9):4526-4542. |