| Description | Br-PEG4-CH2-Boc, a PEG- and Alkyl/ether-based PROTAC linker, serves as a valuable component for the synthesis of PROTACs[1]. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 371.26 |
| Molecular formula | C14H27BrO6 |
| CAS | 1807505-29-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1. |