| Description | Bosentan-d4, the deuterium-labeled variant of Bosentan, serves as a competitive dual antagonist against endothelin-1 (ET) by targeting both ET A and ET B receptors. It exhibits binding affinities with K i values of 4.7 nM for ET A and 95 nM for ET B in human SMC. |
| molecular weight | 555.64 |
| Molecular formula | C27H25D4N5O6S |
| CAS | 1065472-77-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 years |