| Description | Boc-Aminooxy-PEG4-azide is a polyethylene glycol (PEG) derived linker with potential applications in the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 378.42 |
| Molecular formula | C15H30N4O7 |
| CAS | 2100306-64-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413. |