| Description | BMS641 (BMS-209641) is a selective and potent RARβ agonist.BMS641 has a high affinity for RARβ and synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes. |
| Target activity | RARβ:2.5 nM (Kd), RARγ:223 nM (Kd), RARα:225 nM (Kd) |
| Synonyms | BMS-641, BMS-209641, BMS 641 |
| molecular weight | 414.92 |
| Molecular formula | C27H23ClO2 |
| CAS | 369364-50-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 5 mg/mL (12.05 mM), Sonication is recommended. |
| References | 1. Germain P, et al. Rational design of RAR-selective ligands revealed by RARbeta crystal stucture. EMBO Rep. 2004;5(9):877-882. |