| Description | BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation. |
| Synonyms | BMS394136, BMS 394136, BMS394136;UNII-M694U7167K |
| molecular weight | 471.35 |
| Molecular formula | C24H21Cl2FN4O |
| CAS | 343246-73-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (106.08 mM) |
| References | 1. Finlay HJ, et al. Discovery of ((S)-5-(methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone as a potent and selective I(Kur) inhibitor. J Med Chem. 2012 Apr 12;55(7):3036-48. |