| Description | BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction. |
| Synonyms | BMS242 |
| molecular weight | 449.58 |
| Molecular formula | C28H35NO4 |
| CAS | 1675204-51-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Guzik K, Zak KM, Grudnik P, Magiera K, Musielak B, Törner R, Skalniak L, Dömling A, Dubin G, Holak TA. Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1. J Med Chem. 2017 Jul 13;60(13):5857-5867. doi: 10.1021/acs.jmedchem.7b00293. Epub 2017 Jun 23. PubMed PMID: 28613862. 2. Zak KM, Grudnik P, Guzik K, Zieba BJ, Musielak B, Dömling A, Dubin G, Holak TA. Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget. 2016 May 24;7(21):30323-35. doi: 10.18632/oncotarget.8730. PubMed PMID: 27083005; PubMed Central PMCID: PMC5058683. |