| Description | Bisindolylmaleimide XI hydrochloride is an orally active PKC inhibitor with inhibitory effects on PKCα, PKCβI, PKCβII, and PKCγ (IC50s of 9 nM, 28 nM, 31 nM, 37 nM, and 108 nM, respectively). |
| Target activity | PKCβII:31 nM (IC50), PKCβI:28 nM (IC50), PKCα:9 nM (IC50), PKCγ:37 nM (IC50), PKCε:108 nM (IC50) |
| molecular weight | 489.01 |
| Molecular formula | C28H29ClN4O2 |
| CAS | 145333-02-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Soluble Methanol: Soluble |