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Bisindolylmaleimide XI hydrochloride

CAS No.: 145333-02-4

Bisindolylmaleimide XI hydrochloride is an orally active PKC inhibitor with inhibitory effects on PKCα, PKCβI, PKCβII
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Description Bisindolylmaleimide XI hydrochloride is an orally active PKC inhibitor with inhibitory effects on PKCα, PKCβI, PKCβII, and PKCγ (IC50s of 9 nM, 28 nM, 31 nM, 37 nM, and 108 nM, respectively).
Target activity PKCβII:31 nM (IC50), PKCβI:28 nM (IC50), PKCα:9 nM (IC50), PKCγ:37 nM (IC50), PKCε:108 nM (IC50)
molecular weight 489.01
Molecular formula C28H29ClN4O2
CAS 145333-02-4
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: Soluble Methanol: Soluble