| Description | Bisindolylmaleimide I HCl is a specific ATP-competitive PKC inhibitor. |
| Synonyms | GF-109203X HCl, BIS-I HCl, GO-6860 HCl |
| molecular weight | 448.95 |
| Molecular formula | C25H25ClN4O2 |
| CAS | 176504-36-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Girardi BA, Ribeiro DA, Signor C, Muller M, Gais MA, Mello CF, Rubin MA. Spermidine-induced improvement of reconsolidation of memory involves calcium-dependent protein kinase in rats. Learn Mem. 2015 Dec 15;23(1):21-8. doi: 10.1101/lm.039396.115. Print 2016 Jan. PubMed PMID: 26670183; PubMed Central PMCID: PMC4749837. 2. Wang W, Song N, Zhang H, Xie J, Wang J. 6-Hydroxydopamine upregulates iron regulatory protein 1 by activating certain protein kinase C isoforms in the dopaminergic MES23.5 cell line. Int J Biochem Cell Biol. 2012 Nov;44(11):1987-92. doi: 10.1016/j.biocel.2012.07.018. Epub 2012 Jul 27. PubMed PMID: 22846799. 3. Guerra GP, Mello CF, Bochi GV, Pazini AM, Rosa MM, Ferreira J, Rubin MA. Spermidine-induced improvement of memory involves a cross-talk between protein kinases C and A. J Neurochem. 2012 Jul;122(2):363-73. doi: 10.1111/j.1471-4159.2012.07778.x. Epub 2012 May 24. PubMed PMID: 22564082. 4. McBane JE, Santerre JP, Labow R. Effect of phorbol esters on the macrophage-mediated biodegradation of polyurethanes via protein kinase C activation and other pathways. J Biomater Sci Polym Ed. 2009;20(4):437-53. doi: 10.1163/156856209X416467. PubMed PMID: 19228446. |