| Description | Bis(diazoacetyl)butane is a mutagen and traditionally related to radio-mimetic chemical mutagens due to the similarity of appearance of mutagenic action of this mutagen and physical mutagens. It also has anti-tumor and carcinogenic activity. |
| Synonyms | 1,4-Bis-diazoacetylbutane, Supermutagen, 1,4-Bis(diazoacetyl)butane, DAB (mutagen) |
| molecular weight | 194.19 |
| Molecular formula | C8H10N4O2 |
| CAS | 1448-16-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Aslanian MM, Kim AI, Smirnova VA. [Characteristics of the mutagenic action of 1,4-bis-diazoacetylbutane on mature Drosophila melanogaster sperm]. Genetika. 1981;17(4):677-83. Russian. PubMed PMID: 6785154. 2. Shigaeva MKh, Akhmatullina NB, Dzhangalina NK. [Effect of nonmutagenic doses of 1,4-bis-diazoacetylbutane on Streptomyces griseus]. Mikrobiologiia. 1982 Nov-Dec;51(6):993-6. Russian. PubMed PMID: 6818438. 3. Ivanovskiĭ IuA, Kulinich NM. [Stimulating action of gamma irradiation and alkylating compounds on the brine shrimp, Artemia salina. 3. 3H-thymidine and 3H-uridine incorporation into the nauplii of A. salina irradiated or treated with 1-4-bis-diazoacetylbutane at the embryonic diapause stage]. Radiobiologiia. 1980 May-Jun;20(3):414-8. Russian. PubMed PMID: 7406993. 4. Gorbunova NA, Sukharevich ME, Iakovleva EP. [Natural and induced variability of pathogen, producing antifungal antibiotic, imbrimycin]. Antibiot Khimioter. 1998;43(3):3-7. Russian. PubMed PMID: 9606489. |