| Description | Biotinyl tyramide, a biotin derivative, is used for tyramide signal amplification, as a reagent to amplify both in situ hybridization and immunohistochemical signals protocols. |
| Synonyms | 生物素基酪氨酰胺, 维生素苯酚 |
| molecular weight | 363.47 |
| Molecular formula | C18H25N3O3S |
| CAS | 41994-02-9 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (275.13 mM), Sonification is recommended. |
| References | 1. Bobrow MN, et al. Catalyzed reporter deposition, a novel method of signal amplification. Application to immunoassays. J Immunol Methods. 1989 Dec 20;125(1-2):279-85. 2. Kim SH, et al. An improved protocol of biotinylated tyramine-based immunohistochemistry minimizing nonspecific background staining. J Histochem Cytochem. 2003 Jan;51(1):129-32. 3. Evans MF , et al. Optimization of biotinyl-tyramide-based in situ hybridization for sensitive background-free applications on formalin-fixed, paraffin-embedded tissue specimens. BMC Clin Pathol. 2003 Jun 11;3(1):2. 4. Hunyady B, et al. Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining. J Histochem Cytochem. 1996 Dec;44(12):1353-62. |