| Description | Biotin-HPDP (Pyridyldithiol-biotin) is a sulfhydryl reactive biotinylation reagent. |
| Synonyms | Pyridyldisulfide-biotin, Pyridyldithiol-biotin |
| molecular weight | 539.78 |
| Molecular formula | C24H37N5O3S3 |
| CAS | 129179-83-5 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 5.4 mg/ml (10 mM), Sonication is recommended. |
| References | 1. Kim NH, Baek TJ, Park HG, Seong GH. Highly sensitive biomolecule detection on a quartz crystal microbalance using gold nanoparticles as signal amplification probes. Anal Sci. 2007 Feb;23(2):177-81. PubMed PMID: 17297229. 2. Brown RJ, Brett DJ. Electrochemical study of biotin-modified self-assembled monolayers: recommendations for robust preparation. ScientificWorldJournal. 2006 Jan 17;6:20-9. 3. Wan J, Roth AF, Bailey AO, Davis NG. Palmitoylated proteins: purification and identification. Nat Protoc. 2007;2(7):1573-84. 4. Shu W, Laue ED, Seshia AA. Investigation of biotin-streptavidin binding interactions using microcantilever sensors. Biosens Bioelectron. 2007 Apr 15;22(9-10):2003-9. Epub 2006 Oct 12. PubMed PMID: 17045792. |
| Citations | 1. Sun Y, Zhang H, Meng J, et al. S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway. Cell Reports. 2022, 40(7): 111194. |