| Description | BI-1622 is a highly selective, orally active HER2(ERBB2) inhibitor (IC50: 7 nM). BI-1622 is >25-fold selective for EGFR. In a mouse model of transplanted tumors transfected with H2170 and PC9 cells, BI-1622 exhibited high in vivo antitumor effects with good drug metabolism and pharmacokinetic properties. |
| molecular weight | 508.53 |
| Molecular formula | C26H24N10O2 |
| CAS | 2681392-19-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |