| Description | Betamipron (CS-443) is used combination with panipenem to prevent nephrotoxicity and inhibit panipenem uptake into the renal tubule. |
| In vivo | Panipenem是非肠道的碳青霉烯类抗菌剂,对革兰阴/阳性需氧菌和厌氧菌,包括肺炎链球菌和产生β-内酰胺酶的物种均有抗菌活性。 |
| Synonyms | CS-443, N-Benzoyl-β-alanine, 倍他米隆 |
| molecular weight | 193.2 |
| Molecular formula | C10H11NO3 |
| CAS | 3440-28-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | Ethanol: 37 mg/mL (191.5 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 50 mg/mL (258.8 mM), Sonication is recommended. |
| References | 1. Ohashi N, et al. J Infect Chemother, 2005, 11(1), 24-31. 2. Goa KL, et al. Drugs, 2003, 63(9), 913-925. |