| Description | Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic. |
| In vitro | Besifloxacin 在针对广泛及耐药病原体方面展现出了有效的杀菌活性。它在对抗革兰阳性病原体和厌氧菌方面被认为是测试中的高效化合物，并且在对抗大多数革兰阴性病原体方面，其活性普遍与其他比较对象的氟喹诺酮相当。Besifloxacin 展示了强大的广谱活性，特别是对于那些对其他氟喹诺酮和不同类别的抗菌剂耐药的革兰阳性和革兰阴性分离物。 |
| Synonyms | BOL-303224-A, Besivance hydrochloride, Besifloxacin HCl, 盐酸贝西沙星 |
| molecular weight | 430.3 |
| Molecular formula | C19H21ClFN3O3·HCl |
| CAS | 405165-61-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 11 mg/mL (25.56 mM) |
| References | 1. McDonald MB, et al. Ophthalmology, 2009, 116(9), 1615-1623. 2. Haas W, et al, Antimicrob Agents Chemother, 2009, 53(8), 3552-3560. |
| Citations | 1. Kaduk J A, Gates-Rector S, Blanton T N.Crystal structure of besifloxacin hydrochloride, C19H22ClFN3O3Cl.Powder Diffraction.2023: 1-10. |