| Description | Berefrine is an Oxazolidine prodrug of phenylephrine. |
| molecular weight | 235.32 |
| Molecular formula | C14H21NO2 |
| CAS | 105567-83-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Qiu Y, Schoenwald RD, Guillory JK. Physicochemical characterization of high- and low-melting phenylephrine oxazolidines. Pharm Res. 1993 Oct;10(10):1507-15. PubMed PMID: 8272415. 2. Miller-Meeks MJ, Farrell TA, Munden PM, Folk JC, Rao C, Schoenwald RD. Phenylephrine prodrug. Report of clinical trials. Ophthalmology. 1991 Feb;98(2):222-6. PubMed PMID: 2008281. 3. Chien DS, Schoenwald RD. Ocular pharmacokinetics and pharmacodynamics of phenylephrine and phenylephrine oxazolidine in rabbit eyes. Pharm Res. 1990 May;7(5):476-83. PubMed PMID: 2367315. 4. Schoenwald RD, Chien DS. Ocular absorption and disposition of phenylephrine and phenylephrine oxazolidine. Biopharm Drug Dispos. 1988 Nov-Dec;9(6):527-38. PubMed PMID: 3228574. |