| Description | Benzoylaconine (Isaconitine) is an alkaloid in the Chinese traditional medicine Radix Aconiti Lateralis Preparata (Fuzi). Benzoylaconine and aconitine can induce reproductive toxicity in BeWo Cell, the amino acid metabolism was the main metabolic pathway and responsible for the placental and fetal toxicity of them. |
| Synonyms | 苯甲酰乌头原碱, Pikraconitin, Isaconitine, Benzoylaconitine |
| molecular weight | 603.7 |
| Molecular formula | C32H45NO10 |
| CAS | 466-24-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/mL (91.1 mM) |
| References | 1. Liu XX, et al. Determination of alkaloids in Radix Aconiti Lateralis Preparata by RP-ion-pair HPLC. Yao Xue Xue Bao. 2006 Apr;41(4):365-9. 2. Borcsa B, et al. Diterpene alkaloids from the roots of Aconitum moldavicum and assessment of Nav1.2 sodium channel activity of aconitum alkaloids. Planta Med. 2014 Feb;80(2-3):231-6. 3. Dai P , Zhu L , Yang X , et al. Multidrug resistance-associated protein 2 is involved in the efflux of Aconitum alkaloids determined by MRP2-MDCKII cells[J]. Life Sciences, 2015, 127:66-72. |
| Citations | 1. Chen L, Zhang C, Cao J, et al. Yiyi Fuzi Baijiang Decoction Alleviates Ulcerative Colitis Partly by Regulating TLR4-Mediated PI3K/Akt and NF-κB Pathways. Evidence-Based Complementary and Alternative Medicine. 2022, 2022. |