| Description | Benfluralin, a pre-emergence herbicide and agrochemical, is utilized for controlling grass and various weed species in both food and non-food crop applications. |
| In vivo | 对毒理学数据库的审查提供了证据,表明benfluralin导致啮齿动物肝细胞腺瘤和癌症的作用机制(MOA)依赖于激活构成性雄烷(CAR)/孕烷X(PXR)受体,从而触发酶的诱导和基因表达的改变,导致肝细胞增殖[1]。 |
| molecular weight | 335.28 |
| Molecular formula | C13H16F3N3O4 |
| CAS | 1861-40-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 145 mg/mL (432.47 mM), Sonication is recommended. |
| References | 1. Strupp C, Quesnot N, Richert L, Moore J, Bomann WH, Singh P. Weight of evidence and human relevance evaluation of the benfluralin mode of action in rodents (Part I): Liver carcinogenesis. Regul Toxicol Pharmacol. 2020 Nov;117:104758. |