| Description | Benarthin is a pyroglutamyl peptidase (PG-peptidase) inhibitor. |
| molecular weight | 411.41 |
| Molecular formula | C17H25N5O7 |
| CAS | 143651-45-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Hatsu M, Tuda M, Muraoka Y, Aoyagi T, Takeuchi T. Benarthin: a new inhibitor of pyroglutamyl peptidase. III. Synthesis and structure-activity relationships. J Antibiot (Tokyo). 1992 Jul;45(7):1088-95. PubMed PMID: 1355473. 2. Hatsu M, Naganawa H, Aoyagi T, Takeuchi T. Benarthin: a new inhibitor of pyroglutamyl peptidase. II. Physico-chemical properties and structure determination. J Antibiot (Tokyo). 1992 Jul;45(7):1084-7. PubMed PMID: 1355472. 3. Aoyagi T, Hatsu M, Kojima F, Hayashi C, Hamada M, Takeuchi T. Benarthin: a new inhibitor of pyroglutamyl peptidase. I. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo). 1992 Jul;45(7):1079-83. Erratum in: J Antibiot (Tokyo) 1992 Oct;45(10):C5. PubMed PMID: 1355471. |