| Description | Bellidifolin (Bellidifoline) has anti-oxidation, hepatoprotective, anti-inflammatory and antitumor actions, it may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms related to inhibition of cell apoptosis independent of the ERK pathway. Bellidifolin shows interesting inhibitory activity of monoamine oxidases (MAO) A, it could be useful for treating type-2 diabetes, likely via the improvement of insulin resistance (IR). Bellidifolin also shows an antifungal effect (MIC values of 50 microg/mL). |
| Synonyms | Bellidifoline, 龙胆山酮酚, Bellidifolium, 雏菊叶龙胆酮 |
| molecular weight | 274.23 |
| Molecular formula | C14H10O6 |
| CAS | 2798-25-6 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 25 mg/mL (91.17 mM) |
| References | 1. Basnet, P., Kadota, S., Shimizu, M., Takata, Y., Kobayashi, M., & Namba, T. (1995). Bellidifolin Stimulates Glucose Uptake in Rat 1 Fibroblasts and Ameliorates Hyperglycemia in Streptozotocin (STZ)-Induced Diabetic Rats. Planta Medica, 61(05), 402-405. doi: 10.1055/s-2006-958124 2. Basnet, P., Kadota, S., Shimizu, M., & Namba, T. (1994). Bellidifolin: A Potent Hypoglycemic Agent in Streptozotocin (STZ)-Induced Diabetic Rats fromSwertia japonica. Planta Medica, 60(06), 507-511. doi: 10.1055/s-2006-959560 |