| Description | BCPA is a non-cytotoxic Pin1 modulator.BCPA modulates osteoclast activation and attenuates the reduction of Pin1 protein, thereby inhibiting RANKL-induced receptor activators of osteoclastogenesis.BCPA is used in the study of osteoporosis. |
| molecular weight | 417.33 |
| Molecular formula | C22H22Cl2N2O2 |
| CAS | 547731-67-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 1 mg/mL, Sonication is recommended. |
| References | 1. Cho E, et al. BCPA {N, N′-1, 4-Butanediylbis [3-(2-chlorophenyl) acrylamide]} Inhibits osteoclast differentiation through increased retention of peptidyl-prolyl cis-trans isomerase never in mitosis A-interacting International Journal of Molecular Sciences, 2018, 19(11): 3436. |