| Description | BCAT-IN-4 is a potent BCAT inhibitor with an IC50 value of 2.35 μM for hBCATc. BCAT-IN-4 has anticancer activity and can be used to study pancreatic ductal adenocarcinoma. |
| Target activity | BCATc (human):2.35 μM |
| molecular weight | 366.39 |
| Molecular formula | C19H14N2O4S |
| CAS | 406190-85-0 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (136.47 mM) |
| References | 1. Hu LY, et al. The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. |