| Description | BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 192, IC50: 341 nM). It has the potential for cancer treatment. |
| In vitro | BAY 2416964 在人类单核细胞U937细胞中诱导AHR调节的基因CYP1A1表达（IC50：4.3 nM）。 |
| Target activity | AhR:341 nM |
| molecular weight | 387.82 |
| Molecular formula | C18H18ClN5O3 |
| CAS | 2242464-44-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 250 mg/mL (644.63 mM), Sonication is recommended. |
| References | 1. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1 |