| Description | Azodicarbonamide is the first nucleocapsid inhibitor known to inhibit HIV-1 and various retroviruses by targeting the nucleocapsid CCHC domains. In a standard cellular antiviral assay, the compound inhibited HIV-1RF-induced CEM-SS cytopathy with an EC50 value of 38 µM. |
| Target activity | HIV-1 (cell-based assay):38 μM(EC50) |
| Synonyms | NSC 674447, ADA, HPH-116 |
| molecular weight | 116.08 |
| Molecular formula | C2H4N4O2 |
| CAS | 123-77-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Rice WG, et al. Nat Med. 1997 Mar;3(3):341-5. |