| Description | Azido-PEG3-aminoacetic acid-NHS ester is a PEGylation-based linker for the development of PROTACs[1]. It can be utilized in the synthesis of PROTACs, offering a versatile and efficient approach. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 373.36 |
| Molecular formula | C14H23N5O7 |
| CAS | 2170240-91-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
Azido-PEG3-aminoacetic acid-NHS ester
CAS No.: 2170240-91-0
Azido-PEG3-aminoacetic acid-NHS ester is a PEGylation-based linker for the development of PROTACs[1]. It can be utilized
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